Abstract. In this paper we introduce an extension of the PARADIGMA (PARticipative Approach to DIsease Global Management) approach to take into account the home healthcare assistance service. PARADIGMA defines and disseminates a common methodology and optimized protocols (Clinical Pathways) to support service functions directed to patients and individuals on matters like prevention, post-hospitalization support and awareness. Specifically, PARADIGMA will provide a platform of information services - user oriented and optimized against social, cultural and technological constraints - supporting the Health Care Global System in a continuous improvement process.