: Research has found that animated characters are capable of capturing users’ attention, engaging them in active tasks, and entertaining them. Such capabilities are pedagogical techniques that might contribute to an effective comprehensible multimedia presentation. Quality of voice has also been shown to be an important determinant of comprehension. The current study examines the effects of animated characters and voice types on comprehension and attention performance in learning from a multimedia presentation. Because animated characters rely on affective social responses to produce pedagogical benefits, there are also likely to be significant individual differences. This study investigates the influence of introversion/extroversion on the effectiveness of the presentations as well. A 3 (no character, nonanthropomorphic character, anthropomorphic character) x 2 (synthetic voice vs. human voice) factorial between-subject design was employed. While animated characters did not increase...