Large-scale global optimization (LSGO) is a very important and challenging task in optimization domain, which is embedded in many scientific and engineering applications. In this paper, a two-stage based ensemble optimization evolutionary algorithm (EOEA) is designed to handle LSGO problems. The performance of EOEA is evaluated on the test functions provided by the LSGO competition of IEEE Congress of Evolutionary Computation (CEC 2010). Compared with some previous LSGO algorithms, EOEA demonstrates better performance.