Biocompute: towards a collaborative workspace for data intensive bio-science

The explosion of data in the biological community demands the development of more scalable and flexible portals for bioinformatic computation. To address this need, we put forth characteristics needed for rigorous, reproducible, and collaborative resources for data intensive science. Implementing a system with these characteristics exposed challenges in user interface, data distribution, and workflow description/execution. We describe several responses to these challenges. The Data-Action-Queue metaphor addresses user interface and system organization concepts. A dynamic data distribution mechanism lays the foundation for the management of persistent datasets. The Makeflow workflow facilitates the simple description and execution of complex multipart jobs. The resulting web portal, Biocompute, has been in production use at the University of Notre Dame's Bioinformatics Core Facility since the summer of 2009. It has provided over seven years of CPU time through its three sequence s...

• Type: Conference
• Year: 2010
• Where: HPDC
• Authors: Rory Carmichael, Patrick Braga-Henebry, Douglas Thain, Scott J. Emrich
• Keywords: Characteristics Exposed Challenges, Data Distribution, Distributed And Parallel Computing, HPDC 2010, User Interface