Label structured cell proliferation models

We present a general class of cell population models that can be used to track the proliferation of cells which have been labeled with a fluorescent dye. The mathematical models employ fluorescence intensity as a structure variable to describe the evolution in time of the population density of proliferating cells. While cell division is a major component of changes in cellular fluorescence intensity, models developed here also address overall label degradation. Key words: Cell proliferation, label structured population dynamics, partial differential equations, moving coordinate systems. 1 

• Type: Journal
• Year: 2010
• Where: APPML
• Authors: H. T. Banks, Frédérique Charles, Marie Doumic Jauffret, Karyn L. Sutton, W. Clayton Thompson
• Keywords: APPML 2010, Cell Population Models, Cellular Fluorescence Intensity, Fluorescence Intensity