A structured approach for the engineering of biochemical network models, illustrated for signalling pathways

Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Building and managing these complex models is a major challenge that can benefit from the application of formal methods adopted from theoretical computing

• Type: Journal
• Year: 2008
• Where: BIB
• Authors: Rainer Breitling, David Gilbert, Monika Heiner, Richard J. Orton
• Keywords: BIB 2008, Gene Regulatory Circuits, Modern Systems Biology, Quantitative Models