The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images

Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subcellular localization of proteins. Determining the subcellular localization is an integral part of identifying a protein's function, and the application of bioinformatics to this problem provides a valuable tool for the annotation of proteomes. Training and validating algorithms used in image analysis research typically rely on large sets of image data, and would benefit from a large, well-annotated and highly-available database of images and associated metadata. Description: The Yeast Resource Center Public Image Repository (YRC PIR) is a large database of images depicting the subcellular localization and colocalization of proteins. Designed especially for computational biologists who need large numbers of images, the YRC PIR contains 532,182 TIFF images from nearly 85,000 separate experiments and their ...

• Type: Journal
• Year: 2010
• Where: BMCBI
• Authors: Michael Riffle, Trisha N. Davis
• Keywords: BMCBI 2010, Images, Subcellular Localization, YRC PIR