This chapter describes Aneka-Federation, a decentralized and distributed system that combines enterprise Clouds, overlay networking, and structured peer-to-peer techniques to create scalable wide-area networking of compute nodes for high-throughput computing. The Aneka-Federation integrates numerous small scale Aneka Enterprise Cloud services and nodes that are distributed over multiple control and enterprise domains as parts of a single coordinated resource leasing ion. The system is designed with the aim of making distributed enterprise Cloud resource integration and application programming flexible, efficient, and scalable. The system is engineered such that it: enables seamless integration of existing Aneka Enterprise Clouds as part of single wide-area resource leasing federation; self-organizes the system components based on a structured peer-to-peer routing methodology; and presents end-users with a distributed application composition environment that can support variety of prog...