We study two-player games of infinite duration that are played on finite or infinite game graphs. A winning strategy for such a game is positional if it only depends on the current position, and not on the history of the play. A game is positionally determined if, from each position, one of the two players has a positional winning strategy. The theory of such games is well studied for winning conditions that are defined in terms of a mapping that assigns to each position a priority from a finite set C. Specifically, in Muller games the winner of a play is determined by the set of those priorities that have been seen infinitely often; an important special case are parity games where the least (or greatest) priority occurring infinitely often determines the winner. It is well-known that parity games are positionally determined whereas Muller games are determined via finite-memory strategies. In this paper, we extend this theory to the case of games with infinitely many priorities. Such g...