We propose the cross-layer based opportunistic multi-channel medium access control (MAC) protocols, which integrate the spectrum sensing at physical (PHY) layer with the packet scheduling at MAC layer, for the wireless ad hoc networks. Specifically, the MAC protocols enable the secondary users to identify and utilize the leftover frequency spectrum in a way that constrains the level of interference to the primary users. In our proposed protocols, each secondary user is equipped with two transceivers. One transceiver is tuned to the dedicated control channel, while the other is designed specifically as a cognitive radio that can periodically sense and dynamically use the identified un-used channels. To obtain the channel state accurately, we propose two collaborative channel spectrum-sensing policies, namely, the random sensing policy and the negotiation-based sensing policy, to help the MAC protocols detect the availability of leftover channels. Under the random sensing policy, each se...