Trip planning search (TPS) represents an important class of queries in Geographic Information Systems (GIS). In many real-world applications, TPS requests are issued with a number of constraints. Unfortunately, most of these constrained TPS cannot be directly answered by any of the existing algorithms. By formulating each restriction into rules, we propose a novel form of route query, namely the multi-rule partial sequenced route (MRPSR) query. Our work provides a unified framework that also subsumes the well-known trip planning query (TPQ) and the optimal sequenced route (OSR) query. In this paper, we first prove that MRPSR is NP-hard and then present three heuristic algorithms to search for near-optimal solutions for the MRPSR query. Our extensive simulations show that all of the proposed algorithms can answer the MRPSR query effectively and efficiently. Using both real and synthetic datasets, we investigate the performance of our algorithms with the metrics of the route distance an...