High performance workflow implementation for protein surface characterization using grid technology

Background: This study concerns the development of a high performance workflow that, using grid technology, correlates different kinds of Bioinformatics data, starting from the base pairs of the nucleotide sequence to the exposed residues of the protein surface. The implementation of this workflow is based on the Italian Grid.it project infrastructure, that is a network of several computational resources and storage facilities distributed at different grid sites. Methods: Workflows are very common in Bioinformatics because they allow to process large quantities of data by delegating the management of resources to the information streaming. Grid technology optimizes the computational load during the different workflow steps, dividing the more expensive tasks into a set of small jobs. Results: Grid technology allows efficient database management, a crucial problem for obtaining good results in Bioinformatics applications. The proposed workflow is implemented to integrate huge amounts of...

• Type: Journal
• Year: 2005
• Where: BMCBI
• Authors: Ivan Merelli, Giulia Morra, Daniele D'Agostino, Andrea Clematis, Luciano Milanesi
• Keywords: BMCBI 2005, Grid Technology, Protein Surface, Workflow