: This paper describes the development of the sensor interface and driver program for a point of care (POC) device. The proposed POC device comprises an ARM9 embedded processor and eightchannel sensor input to measure various bio-signals. It features a user-friendly interface using a fullcolor TFT-LCD and touch-screen, and a bluetooth wireless communication module. The proposed device is based on the system on a programmable chip (SOPC). We use Altera’s Excalibur device, which has an ARM9 and FPGA area on a chip, as a test bed for the development of interface hardware and driver software.