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2002

Beyond spike timing: the role of nonlinear plasticity and unreliable synapses

13 years 10 months ago
Beyond spike timing: the role of nonlinear plasticity and unreliable synapses
Spike-timing-dependent plasticity (STDP) strengthens synapses that are activated immediately before a postsynaptic spike, and weakens those that are activated after a spike. To prevent an uncontrolled growth of the synaptic strengths, weakening must dominate strengthening for uncorrelated spike times. However, this weight-normalization property would preclude Hebbian potentiation when the pre- and postsynaptic neurons are strongly active without specific spike-time correlations. We show that nonlinear STDP as inherent in the data of Markram et al. [(1997) Science 275:213
Walter Senn
Added 16 Dec 2010
Updated 16 Dec 2010
Type Journal
Year 2002
Where BC
Authors Walter Senn
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