Grid technology has evolved over the past several years to provide the services and infrastructure needed for building "virtual" systems and organizations. With this Grid based infrastructure that provides for using and managing widely distributed computing and data resources in the science environment, there is now an opportunity to provide a standard, large-scale, computing, data, instrument, and collaboration environment for science that spans many different projects, institutions, and countries. We argue that Grid technology provides an excellent basis for the creation of the integrated environments that can combine the resources needed to support the large-scale science projects located at multiple laboratories and universities. We also present some science case studies that indicate that a paradigm shift in the process of science will come about as a result of Grids providing transparent and secure access to advanced and integrated information and technologies infrastr...
William E. Johnston