The Perfect C. elegans Project: An Initial Report

The soil nematode Caenorhabditis Elegans (C. elegans) is the most investigated of all multi-cellular organisms. Since the proposal to use it as a model organism, a series of research projects have been undertaken, investigating a wide range of on various aspects of this organism. As a result, the complete cell lineage, neural circuitry, and various genes and their functions have been identified. The complete C. elegans DNA sequencing and gene expression mapping for each cell at different times during embryogenesis will be identified in a few years. Given the abundance of collected data, we believe that the time is ripe to introduce synthetic models of C. elegans to further enhance our understanding of the underlying principles of its development and behavior. For this reason, we have started the Perfect C. elegans Project, which aims to ultimately produce a complete synthetic model of C. elegans cellular structure and function. This paper describes the goal, the approach, and the in...

• Type: Journal
• Year: 1998
• Where: ALIFE
• Authors: Hiroaki Kitano, Shugo Hamahashi, Sean Luke
• Keywords: ALIFE 1998, Elegans, Elegans Dna, Modeling And Simulation, Synthetic Model