Nanobiosensors based on individual olfactory receptors

In the framework of the SPOT-NOSED European project, nanoscale sensing elements bearing olfactory receptors and grafted onto functionalized gold substrates are used as odorant detectors to develop a new concept of nanobioelectronic nose, through sensitive impedancemetric measurement of single receptor conformational change upon odorant ligand binding, with a better specificity and lower detection thresholds than traditional physical sensors.

• Type: Journal
• Year: 2008
• Where: CORR
• Authors: E. Pajot-Augy
• Keywords: CORR 2008, Education, Nanoscale Sensing Elements, Sensitive Impedancemetric Measurement, SPOT-NOSED European Project