Based on independent component analysis (ICA) and self-organizing maps (SOM), this paper proposes an ISOM-DH model for the incomplete data’s handling in data mining. Under these circumstances the data remain dependent and non-Gaussian, this model can make full use of the information of the given data to estimate the missing data and can visualize the handled high-dimensional data. Compared with mixture of principal component analyzers (MPCA), mean method and standard SOM-based fuzzy map model, ISOM-DH model can be applied to more cases, thus performing its superiority. Meanwhile, the correctness and reasonableness of ISOM-DH model is also validated by the experiment carried out in this paper. Keywords Incomplete data Æ ICA (independent component analysis) Æ SOM (self-organizing maps) Æ Dependence Æ Non-Gaussian distribution