—The conventional teaching model is broken in Mode CDIO, in which, with the carrier of project, the educational idea based on project-learning and the principle of teaching integration are embodied, and students play main roles well, while faculty play leading rolls. Taking Principle and Application of Single-chip Computer as an example, we expatiate on the implementation of the teaching reform in Mode CDIO and get an improved teaching quality. Keywords-Mode CDIO; single-ship computer; curriculum reform; project-based learning