Future systems will have to support multiple and concurrent dynamic compute-intensive applications, while respecting real-time and energy consumption constraints. To overcome these computation needs, only multithreaded approaches are possible. Thus, the support of a streaming execution model is very important for dataflow applications. However, with dynamic applications, each execution stage is prone to execution time variations. The sizing of these highly complex MPSoC architectures becomes difficult. In such a context, flexible and accurate simulators become a necessity for exploring the vast design space solution. In this paper, we use the SESAM environment to ease the architectural exploration of asymmetric MPSoCs for dynamic streaming application processing. This paper focuses on the new programming and execution model supported by the simulator, and studies performances obtained with a WCDMA encoder/decoder application implemented on a complete MPSoC platform.