It has recently been shown that greater accuracy in fMRI processing can be achieved if registration and activation detection are solved simultaneously rather than in sequence. However, this simultaneous solution has been demonstrated only for fMRI experiments in which a single stimulus condition was used. This paper presents results obtained by applying the simultaneous solution technique to simulated datasets with two stimulus conditions, and demonstrates that the technique is equally effective on such datasets.
Jeff Orchard, M. Stella Atkins