The notion of three-way decisions was originally introduced by the needs to explain the three regions of probabilistic rough sets. Recent studies show that rough set theory is only one of possible ways to construct three regions. A more general theory of three-way decisions has been proposed, embracing ideas from rough sets, interval sets, shadowed sets, three-way approximations of fuzzy sets, orthopairs, square of oppositions, and others. This paper presents a trisecting-and-acting framework of three-way decisions. With respect to trisecting, we divide a universal set into three regions. With respect to acting, we design most effective strategies for processing the three regions. The identification and explicit investigation of different strategies for different regions are a distinguishing feature of three-way decisions.