As our technologies travel to new cultural contexts and our designs and methods engage new constituencies, both our design and analytical practices face significant challenges. We offer postcolonial computing as an analytical orientation to better understand these challenges. This analytic orientation inspires four key shifts in our approach to HCI4D efforts: generative models of culture, development as a historical program, uneven economic relations, and cultural epistemologies. Then, through reconsideration of the practices of engagement, articulation and translation in other contexts, we offer designers and researchers ways of understanding use and design practice to respond to global connectivity and movement. Author Keywords Postcolonial theory, STS, culture, design methods, ICT4D. ACM Classification Keywords H5.m. Information interfaces and presentation (e.g., HCI): Miscellaneous.