—Transmitter Leakage has a significant impact on the system performance in mobile devices using zero-IF receivers. In this contribution, the statistical properties of the Tx Leakage impact in zero-IF receivers are derived, in the context of Uplink and Downlink OFDM transmission. In order to design suitable algorithms for the digital compensation of Tx Leakage in OFDM communication systems, an accurate modeling of the corresponding performance loss is required. We therefore provide a statistical description of Tx Leakage effects on OFDM signals, which is used to compute bit error rates and mutual information.