In this paper, we present a proposal for Patients’ Mobile Monitoring. This framework enables the definition and generation of profiles, modules and communication structures between each of the measuring devices and the mobile phone depending on the kind of condition and the measuring values of the patient. We use patterns to allow the generation of self-control modules and patient profiles. These patterns establish relations between each module. With patient’s measured data, patient profile and modules, the framework generates an application for the doctor and the patient in a mobile phone. These applications allow the monitoring, patient self-control and the communication between the patient and the doctor. Moreover, as an important study case, we present a mobile monitoring system which allows patients with diabetes to have a constant control of their glucose tendency as well as direct communication with their doctor.