—In this paper, we propose an analytical technique to evaluate the statistics of the channel estimation error in a simple multi-user ad hoc networking scenario. This problem is very relevant in situations where advanced PHY techniques are used (e.g., MIMO or interference cancellation) and channel state information may be needed. The presence of several simultaneous and non-orthogonal signals makes the problems significantly more complicated than in traditional channel estimation. In particular, there is direct dependence of the channel estimation error on the instantaneous channel matrix. The proposed model makes it possible to quickly evaluate the performance of channel estimation schemes as a function of the system parameters. In this light, we include the effect of channel estimation errors in an ad hoc networking protocol simulator and thoroughly evaluate their impact. Our results show that there exists a significant interplay between the performance of MAC protocols for MIMO n...