This paper introduces a generalized cross-correlation (GCC) measure for spike train analysis derived from reproducing kernel Hilbert spaces (RKHS) theory. An estimator for GCC is derived that does not depend on binning or a specific kernel and it operates directly and efficiently on spike times. For instantaneous analysis as required for real-time use, an instantaneous estimator is proposed and proved to yield the GCC on average. We finalize with two experiments illustrating the usefulness of the techniques derived.
António R. C. Paiva, Il Park, Jose C. Princ