Abstract. Healthcare knowledge management is an active, yet not a well characterized research topic. In this chapter, we attempt to characterize healthcare knowledge management and highlight the practical aspects of healthcare knowledge management vis-à-vis knowledge-centric services that aim to improve healthcare delivery and health outcomes. We investigate healthcare knowledge management from various perspectives--such as epistemological, organizational learning, knowledge-theoretic and functional. From an epistemological perspective we elicit the different types of healthcare knowledge and the heterogeneous modalities representing it. From a functional perspective we present a suite of healthcare knowledge management services that aim to assist healthcare stakeholders. From a knowledge-theoretic perspective, we present the frontiers of healthcare knowledge management, in particular for patient management through decision support and care planning via a Semantic Web based healthcare...