Abstract. We propose and discuss foundations for programmable overlay networks and overlay computing systems. Such overlays are built over a large number of distributed computational individuals, virtually organized in colonies, and ruled by a leader (broker) who is elected or imposed by system administrators. Every individual asks the broker to log in the colony by declaring the resources that can be offered (with variable guarantees). Once logged in, an individual can ask the broker for other resources. Colonies can recursively be considered as evolved individuals who can log in an outermost colony governed by another (super)-broker. Communications and routing intra-colonies goes through a broker-2-broker PKI-based negotiation. Every broker routes intra- and inter- service requests by filtering its resource routing table, and then by forwarding the request first inside its colony, and second outside, via the proper super-broker (thus applying an endogenous-first-estrogen-last str...