Abstract- We present an architecture and VLSI implemen- Various strategies in the analysis of spatio-temporal dynamtation of a distributed neural interface and spatio-temporal ics of the neuronal activity have been developed. Examples of signal processor. The integrated neural interface records neural such analysis include cross-correlation, spectral analysis [9] activity simultaneously on 256 voltage-mode channels. Each . . . channel implements differential signal acquisition, amplification and population vector analysis [10]. To date, brain actvity and band-pass filtering. An array of in-channel double-memory analysis techniques have been implemented off-chip, on a sample-and-hold cells stores two 16 x 16 electronic images stationary computer or an additional high-throughput digital of distributed neural activity consecutively in time. A column- processor. Integrated neural interfaces allow for local onparallel double sampling circuit performs frame differencing chip intelligent spat...
J. N. Y. Aziz, Roman Genov, B. R. Bardakjian, M. D