We describe the Biomolecule Stretching Data Base that has been recently set up at http://www.ifpan .edu.pl/BSDB/. It provides information about mechanostability of proteins. Its core is based on simulations of stretching of 17 134 proteins within a structure-based model. The primary information is about the heights of the maximal force peaks, the force–displacement patterns, and the sequencing of the contact-rupturing events. We also summarize the possible types of the mechanical clamps, i.e. the motifs which are responsible for a protein’s resistance to stretching.
Mateusz Sikora, Joanna I. Sulkowska, Bartlomiej S.