Enterprises today wish to manage their IT resources so as to optimize business objectives, such as income, rather than IT metrics, such as response times. Therefore, we introduce a new paradigm, which focuses on such business objective oriented resource management. Additionally, we define a general simulation-based autonomous process enabling such optimizations, and describe a case study, demonstrating the usefulness of such a process. Categories & Subject Descriptors: C.4 [Performance of Systems]: Modeling techniques and Performance attributes. I.6 [Simulation and Modeling]: I.6.3 Applications and I.6.4 Model Validation and Analysis. General Terms: Management, Measurement, Performance, Economics.