CCDB: a curated database of genes involved in cervix cancer

The Cervical Cancer gene DataBase (CCDB, http:// crdd.osdd.net/raghava/ccdb) is a manually curated catalog of experimentally validated genes that are thought, or are known to be involved in the different stages of cervical carcinogenesis. In spite of the large women population that is presently affected from this malignancy still at present, no database exists that catalogs information on genes associated with cervical cancer. Therefore, we have compiled 537 genes in CCDB that are linked with cervical cancer causation processes such as methylation, gene amplification, mutation, polymorphism and change in expression level, as evident from published literature. Each record contains details related to gene like architecture (exon–intron structure), location, function, sequences (mRNA/CDS/protein), ontology, interacting partners, homology to other eukaryotic genomes, structure and links to other public databases, thus augmenting CCDB with external data. Also, manually curated literature...

• Type: Journal
• Year: 2011
• Where: NAR
• Authors: Subhash M. Agarwal, Dhwani Raghav, Harinder Singh, G. P. S. Raghava
• Keywords: Cervical Carcinogenesis, Cervix Cancer, NAR 2011, Sequence Similarity Search