–Minimally invasive surgery (MIS) is a specialized surgical technique, the minimally invasive surgery compared to traditional surgery, not only can reduce the patient's pain, more can make the patients recover more quickly. But because the minimally invasive surgery is very complex, so the doctors need a lot of training to guarantee the realization of the surgery. In previous studies, we have developed a virtual reality training system. Based on CT image reconstruction of 3-d vessel model, we designed a 3 d model of the catheter. In order to provide the surgeon to meet the need of training sense of touch, we studied the force feedback and the collision detection algorithm. We design a system that contains three kinds of force: force feedback viscous force, friction force and impact force. Catheter force and viscous force between blood; Friction between the catheters means the power of the body and blood vessels; Catheter tip is the collision force between force and vessel. Then ...