Detecting overlapping coding sequences in virus genomes

Background: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding and noncoding functional elements, which can result in unusual patterns of codon usage; conservation between related sequences can be difficult to interpret

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Andrew E. Firth, Chris M. Brown
• Keywords: BMCBI 2006, CDSs, Likelihood Overlapping Gene, Open Reading Frame