Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
Background: Inference of population stratification and individual admixture from genetic markers is an integrative part of a study in diverse situations, such as association mappi...
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...
Background: With the advances in DNA sequencer-based technologies, it has become possible to automate several steps of the genotyping process leading to increased throughput. To e...
B. Jayashree, Praveen T. Reddy, Y. Leeladevi, Jona...
Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf...
Andreas Keller, Nicole Ludwig, Nicole Comtesse, An...