Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow

Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they are required to keep in formats suitable for subsequent data mining. Therefore, a well-developed open source laboratory information management system (LIMS) should be available for their proteomics research studies. Results: We developed an open source LIMS appropriately customized for 2-D gel electrophoresis-based proteomics workflow. The main features of its design are compactness, flexibility and connectivity to public databases. It supports the handling of data imported from mass spectrometry software and 2-D gel image analysis software. The LIMS is equipped with the same input interface for 2-D gel information as a clickable map on public 2DPAGE databases. The LIMS allows researchers to follow their own experimental procedures by reviewing the illustrations of 2-D gel maps and well layouts on the digest...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Hiraku Morisawa, Mikako Hirota, Tosifusa Toda
• Keywords: 2-D Gel, BMCBI 2006, LiMS, Open Source