A general-purpose deformable registration algorithm referred
to as ”DRAMMS” is presented in this paper. DRAMMS adds to the
literature of registration methods that bridge between the traditional
voxel-wise methods and landmark/feature-based methods. In particular,
DRAMMS extracts Gabor attributes at each voxel and selects the
optimal components, so that they form a highly distinctive morphological
signature reflecting the anatomical context around each voxel in
a multi-scale and multi-resolution fashion. Compared with intensity or
mutual-information based methods, the high-dimensional optimal Gabor
attributes render different anatomical regions relatively distinctively
identifiable and therefore help establish more accurate and reliable correspondence.
Moreover, the optimal Gabor attribute vector is constructed
in a way that generalizes well, i.e., it can be applied to different registration
tasks, regardless of the image contents under registration. A
second character...