On error-tolerant DNA screening

Given n clones with some positive ones, the problem of DNA screening is to identify all positive clones with a set of tests each on a subset of clones, called a pool and the outcome is either the pool contains a positive clone or not. In this paper, we show that for a class of designs, if we apply those for samples with d positive clones to samples with at most d -1 positive clones, the error-tolerant property will have an interesting improvement. We also make a remark on decoding method for k-error-correcting d-disjunct matrix.

• Type: Journal
• Year: 2006
• Where: DAM
• Authors: Weili Wu, Yaochun Huang, Xiao Huang, Yingshu Li
• Keywords: -1 Positive Clones, DAM 2006, Positive Clones, Positive Ones