Finding Molecular Signature of Prostate Cancer: An Algorithmic Approach

123 African American men in America are 65% more likely to develop prostate cancer and are two to three times more likely to die of the disease than Caucasian men [1]. While research indicates a strong hereditary link in prostate cancer, it has been difficult to pin down the exact genes involved in this disease. Many men develop prostate cancer later in life, and some men may die before prostate cancer even develops, making it difficult to trace the disease through generations of families [2]. Current research efforts in the testing and detecting of various forms of cancer such as breast and prostate cancer have taken new directions [3]. This paper addresses the genetic predispositions or biomarkers that lead or contribute to such diseases, the application of statistical approaches to researching the biomarkers, and a proposed validation process to mitigate the problem using data mining and high-performance computing techniques.

• Type: Conference
• Year: 2006
• Where: BIOCOMP
• Authors: Patrick Bobbie, Renee Reams, Sandra Suther, C. Perry Brown
• Keywords: African American Men, BIOCOMP 2006, BIOCOMP 2007, Men Develop Prostate, Prostate Cancer