Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f

Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environment, can play an important role in regulating chromosomal processes such as transcription, replication and recombination. The availability of whole-genome sequences has allowed us to annotate the genome environment of any locus in detail. The development of genome wide experimental analyses of gene expression, chromatin modification and chromatin proteins means that it is now possible to identify potential links between chromosomal processes and the underlying genome environment. There is a need for novel bioinformatic tools that facilitate these studies. Results: We developed the Genome Environment Browser (GEB) in order to visualise the integration of experimental data from large scale high throughput analyses with repeat sequence features that define the local genome environment. The browser has incorpora...

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, Sarah Butcher, Neil Brockdorff
• Keywords: BMCBI 2008, Genome Environment, Genome Environment Browser, Local Genome Environment