BMCBI
2008
13 years 10 months ago
2008
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
BMCBI
2008
13 years 10 months ago
2008
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
BMCBI
2008
13 years 10 months ago
2008
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
BMCBI
2008
13 years 10 months ago
2008
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
BMCBI
2008
13 years 10 months ago
2008
Background: Microsatellite (simple sequence repeat
BMCBI
2008
13 years 11 months ago
2008
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
BMCBI
2008
13 years 11 months ago
2008
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
BMCBI
2008
13 years 11 months ago
2008
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
BMCBI
2008
13 years 11 months ago
2008
Background: Automated extraction of protein-protein interactions (PPI) is an important and widely studied task in biomedical text mining. We propose a graph kernel based approach ...
BMCBI
2008
13 years 11 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...