In this paper, we present an integrated system for skin deformation that is able to handle deformations due to both the skeleton animation and collisions. This method is based on a physically-based deformation of a skin surface linked to a reference shape; the reference shape is animated with a geometric deformation. Collision detection has been implemented to avoid penetration. Our method for collision response consists of a kinematical correction of positions and forces during the simulation. The resulting model of the skin deformation enables an efficient simulation and interaction of the skin with deformable objects. Results are presented at the end of the paper as examples.