NullHap - a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles

Background: Laboratory techniques used to determine haplotypes are often too expensive for large-scale studies and lack of phase information is commonly overcome using likelihood-based calculations. Whereas a number of programs are available for that purpose, none of them can handle loci with both multiple and null alleles. Results: Here we present a description of a modified Expectation

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Robert M. Nowak, Rafal Ploski
• Keywords: BMCBI 2008, Haplotype, Laboratory Techniques, Large-scale Studies