Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology

Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity and robustness. The richness in bio-ontologies is a prior condition for diverse and efficient reasoning, and hence querying and hypothesis validation. Rigour allows a more consistent maintenance. Modelling such bio-ontologies is, however, a difficult task for bio-ontologists, because the necessary richness and rigour is difficult to achieve without extensive training. Results: Analogous to design patterns in software engineering, Ontology Design Patterns are solutions to typical modelling problems that bio-ontologists can use when building bio-ontologies. They offer a means of creating rich and rigorous bio-ontologies with reduced effort. The concept of Ontology Design Patterns is described and documentation and application methodologies for Ontology Design Patterns are presented. Some real-world use cases of O...

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Mikel Egaña Aranguren, Erick Antezana, Martin Kuiper, Robert Stevens
• Keywords: BMCBI 2008, Cell Cycle Ontology, Ontology Design Patterns, Rigorous Bio-ontologies