PDBselect 1992-2009 and PDBfilter-select

PDBselect (http://bioinfo.tg.fh-giessen.de/pdb select/) is a list of representative protein chains with low mutual sequence identity selected from the protein data bank (PDB) to enable unbiased statistics. The list increased from 155 chains in 1992 to more than 4500 chains in 2009. PDBfilter-select is an online service to generate user-defined selections. In 1992, bioinformatics was a tiny discipline in statu nascendi. Neither existed bioinformatics as a university discipline nor were the skills shaped, which are required to work at the edge between biology and computer science. Chris Sander's group at EMBL-Heidelberg was one of the few bioinformatics groups in Europe and consisted mainly of biologists and a few physicists. Programming abilities of those days bioinformaticians were self-aquired, the time slice needed for debugging within a programming project usually was considerable and the programming tools were in its infancy. Programs were edited in emacs and debugged from th...

• Type: Journal
• Year: 2010
• Where: NAR
• Authors: Sven Griep, Uwe Hobohm
• Keywords: Low Mutual Sequence, NAR 2010, Protein Data Bank, Representative Protein Chains