We present a vision and preliminary results for a combined RF-Biological Systems where the Electro-Magnetic energy of RF signals is transduced into control-signals for biological signaling-processes. We show how such systems can be used to build extremely low-power sensor networks. We present our approach and propose a system architecture constituted of a passive RF Front End (RF-FE), Bio-Mechanical Signal Interpreter (BMSI), and a Low Power Sensor Node. We show preliminary results for the performance of our RF-FE prototype, outline design alternatives for the BMSI, and summarize theoretical results for characterizing the BMSI components performance. Key words: RF, biological system, wireless sensors, energy harvesting