SBEAMS-Microarray: database software supporting genomic expression analyses for systems biology

Background: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automation of this information extraction requires high throughput management and analysis of genomic expression data, and integration of these data with other data types. Results: SBEAMS-Microarray, a module of the open-source Systems Biology Experiment Analysis Management System (SBEAMS), enables MIAME-compliant storage, management, analysis, and integration of high-throughput genomic expression data. It is interoperable with the Cytoscape network integration, visualization, analysis, and modeling software platform. Conclusion: SBEAMS-Microarray provides end-to-end support for genomic expression analyses for network-based systems biology research. Background The extraction of biological information from high throughput genomic expression data is a fundamentally network-based systems biology problem [1]. Complex ce...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Bruz Marzolf, Eric W. Deutsch, Patrick Moss, David Campbell, Michael H. Johnson, Timothy Galitski
• Keywords: BMCBI 2006, Genomic Expression, Genomic Expression Analyses, Genomic Expression Data