Mobile code solutions can improve the performances of applications over the Internet by reducing the amount of data that must be transferred across the network. The research on genome examines enormous amount of data stored on many distributed databases to retrieve the information relevant for the specific investigation, and thus is likely to greatly benefit for mobile code solutions. This paper studies the benefits of mobile code solutions for research on genome, by comparing different solutions with analytical models, and presenting the results of case studies that allow to identify when mobile code overwhelm client/server solutions. The measured improvements of performance indicate that the retrieval of information from genome databases is a promising domain for mobile code applications.