SimHap GUI: An intuitive graphical user interface for genetic association analysis

Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-friendly graphical analysis tools, requiring sophisticated statistical and informatics expertise to perform relatively straightforward tasks. Tools, such as the SimHap package for the R statistics language, provide the necessary statistical operations to conduct sophisticated genetic analysis, but lacks a graphical user interface that allows anyone but a professional statistician to effectively utilise the tool. Results: We have developed SimHap GUI, a cross-platform integrated graphical analysis tool for conducting epidemiological, single SNP and haplotype-based association analysis. SimHap GUI features a novel workflow interface that guides the user through each logical step of the analysis process, making it accessible to both novice and advanced users. This tool provides a seamless interface to the SimHap ...

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
• Keywords: Analysis, BMCBI 2008, Genetic Association Analysis, Graphical Analysis Tool